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Although GLP-1R agonists exhibit protective and regulatory effects on blood glucose levels, they have been positively correlated with tumor progression in patients with diabetes [51, 73]

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That includes endocrinologists

A striking example: In one Minnesota school district, GLP-1s account for just 2 percent of prescriptions but a staggering 56 percent of total drug spending

GLP1RAs can inhibit neutral lipid accumulation, ROS generation, and (NADPH oxidase 4) NOX-4 expression in rat cardiomyocytes, thereby migrating interleukin-1 (IL-1 ) induced ROS production [57]