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JAMA, 325 (14), 1403-1413

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As access to these pills has tapered off, heroin use has risen

It upregulates genes involved in repair, antioxidant defense, and stem cell function while downregulating genes associated with inflammation, fibrosis, and tissue destruction

doi: 10.1073/pnas.2024852118 31 MahnkeYDGreenwaldJHDerSimonianRRobyGAntonelliLRSherAet al

Vyunova T, Andreeva L, Shevchenko K, Myasoedov N: Peptide-based anxiolytics: The molecular aspects of heptapeptide selank biological activity