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In patients with AECOPD, the abundance of Clostridium intestinalis decreases, reducing butyrate production and thereby limiting its inhibitory effect on intestinal ILC2 activation to iILC2
In a similar study of BALB/c mice sensitized to ovalbumin, reductions in the GSH/GSSG ratio in lung tissue after ovalbumin challenge were also associated with increased airway mucin production and airway hyperresponsiveness, which persisted for several days after the initial exposure (249)
R.BeattyW
Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and autophagy by PI3K/AKT/mTOR and AMPK/mTOR pathway
Bakker J, Lin X and Nelson WG
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