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Skin Health: Reduces melanin production, which helps diminish dark spots and improve overall skin tone

In the context of myelinated axons, we propose that myelin lipid pools represent a conditional buffer because their mobilization requires a specific convergence of constraints: reduced effective glucose supply, partially preserved oxygen availability, and sufficient mitochondrial capacity to metabolize lipid-derived substrates without causing disproportionate oxidative damage

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To address this last shortcoming, we recently modelled the structure of ChaC1 and also mapped the active site (14)

Female sex is overrepresented in idiopathic MCAS, underscoring the need for research regarding the underlying mechanisms and genetic/hormonal alterations in MCA

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