The most common were gastrointestinal-related, including nausea, constipation and diarrhea
Phosphodiesterase-5 inhibitors such as sildenafil are generally safe to use alongside GLP-1 medications, though they are contraindicated with nitrates and should be used cautiously in certain cardiovascular conditions
Doctors prescribing Ozempic off-label for weight loss typically follow the same titration schedule as Wegovy but stop at 2 mg instead of 2.4 mg
These outcomes are clinically significant, as even modest weight loss can lead to meaningful improvements in metabolic health
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The difference is hours, not days, so it primarily affects the acute post-injection experience rather than overall weekly efficacy