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Parallel clinical studies show that omnivores have higher circulating concentrations of l-carnitine than vegans or vegetarians, and that elevated plasma concentrations of l-carnitine in subjects is associated with incident CVD risks (e.g., heart attack, stroke, and death) independent of traditional CVD risk factors, but only in the presence of elevated TMAO (6)

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Although 10 mg/kg/day has been used at these levels of GFR, cases of optic atrophy have been reported

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