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GLP-1 stands for glucagon-like peptide-1, a hormone involved in blood sugar regulation and appetite control

Consistent with a role of vagal afferents and vagal afferent GLP-1 receptors in the eating-inhibitory effect of peripheral endogenous GLP-1, virus-mediated knockdown of GLP-1R in vagal afferent neurons increased meal size, accelerated gastric emptying, and reduced prandial insulin secretion in rats, while not affecting 24 h food intake or body weight [518]

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Over the same period, the number of sleep apnea diagnoses per 1,000 patients rose to 11 from 8 and the number of cardiovascular disease diagnoses increased to 15 from 13

The mean duration of type 2 diabetes mellitus was 3.5 years and the mean BMI was 32 kg/m2