This is where behavioral strategies matter most
The active peptide degrades silently
Click here to listen to all podcast episodes
First-Line, Second-Line, and Alternative Approaches First-Line Options: Lifestyle modification (calorie tracking, physical activity) GLP-1/GIP medications (e.g., Zepbound, Mounjaro) Second-Line: Semaglutide (Wegovy/Ozempic) Liraglutide (Saxenda) Phentermine-topiramate Alternative (or Adjunctive): Metformin (for insulin resistance/PCOS) Bupropion-naltrexone (appetite regulation) Bariatric surgery (in select patients) At Health Express Clinics, we tailor treatment based on individual metabolic profiles, access to medications, and patient goals
doi:10.1080/14740338.2023.1163965 Dahl, D., Onishi, Y., Norwood, P., Huh, R., & Bray, R
In the SURMOUNT-5 trial, tirzepatide produced an average weight reduction of 20.2% (about 50 lbs) over 72 weeks, compared with 13.7% (about 33 lbs) for injectable semaglutide