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However, all other things being equal for a given metal and ligand donor ability, small ligands allow higher coordination numbers while fewer bulky ligands will fit around the metal center

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But it is not produced by our body naturally due to a loss-of-function mutation in the gulo gene encoding L- gulonolactose oxidase, involved in the biochemical pathway synthesizing vitamin C from glucose [1]

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However, we found that four genes, IL-1, IL8, HSPA1A and FOSL1, were significantly induced by CuCl 2 and Cu(OAc) 2 without inhibiting the cell viability