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Diabetologia 52(6):10191026 Hamman RF, Wing RR, Edelstein SL et al (2006) Effect of weight loss with lifestyle intervention on risk of diabetes
No impairment of glucose metabolism
Taken together, dysbiosis contributes to -cell dysfunction through three mutually reinforcing mechanisms: LPS/TLR4-mediated inflammation, insulin-resistancedriven -cell exhaustion, and reduced SCFA availability with consequent weakening of incretin signaling
Key Benefits: Improved Patient Safety : Reduce the risk of dosing errors, especially during dose titration periods
There are other very rare side effects like pancreatitis, gallbladder disease, kidney injury, and suicidal ideation
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