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doi: 10.1038/s41598-022-04880-1 10 ChevalierRL

The global burden of multiple chronic conditions: a narrative review

While numerous probes have shown high sensitivity toward GSH, their selectivity over other thiols such as cysteine and homocysteine remain a major limitation

128 Additionally, thalidomide inhibits M1 macrophage polarization by targeting the transcription factor IRF5, reduces the release of inflammatory signals, significantly reduces the secretion of the proinflammatory cytokines IL-12 and IFN-, and promotes intestinal mucosal healing