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Both PKA inhibitors (Rp-cAMP and H-89) and PI3 kinase inhibitors (LY294002 and wortmannin) partially suppressed the anti-apoptotic effect of GLP-1 on MG-induced apoptosis in both INS-1 and MIN6 cells (Fig

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Both activate the same receptors, so stacking them increases the risk of side effects without necessarily improving efficacy

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The read mapping, variant calling and joint variant calling were performed using Sentieons DNASeq pipeline v.201808.03, following the BWA-GATK Best Practice Workflow and using the GRCh38/hg38 reference genome

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