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For the Screen Positive Rate for SDOH measure, we estimated a total annual burden of 533 hours at a cost of $29,518 in the Hospital OQR Program (89 FR 94524), 6 hours at a cost of $332 in the REHQR Program (89 FR 94531 and 94532), and 746 hours at a cost of $41,313 in the ASCQR Program (89 FR 94535), to report the measure data

Validate key regulators (e.g., cell type-specific lncRNAs and lipid metabolic enzymes) using kidney organoid models, particularly patient-derived organoids (PDOs) that recapitulate disease-specific phenotypes (e.g., diabetic nephropathy and focal segmental glomerulosclerosis)