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The biologically active form of glutathione is its reduced thiol form (GSH), which is oxidized to glutathione disulfide (GSSG) during the neutralization of reactive species

Although high expression of TXNDC12 can play a role in tumors, a study revealed that low mRNA levels of TXNDC12 can also play a suggestive role in the poor prognosis of lung adenocarcinoma patients [20]

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