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Sitting at a desk for extended periods may cause pain, especially when you cannot elevate the affected limb or change positions

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However, gastrointestinal side effects such as nausea, vomiting, and diarrhoea can lead to dehydration, which may precipitate acute kidney injury if fluid intake is inadequate

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Their effect can wear off, however, and repeated use is not suitable for every knee

General heart and immune health: 23 g per day