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Chen Z, Zhang D, Yue F, Zheng M, Kovacevic Z, Richardson DR

In controlled studies, glutathione supplementation increased peroxisome proliferator-activated receptor- coactivator-1 (PGC-1) protein levels by 25% and mitochondrial DNA biogenesis by 53% in skeletal muscle, indicating enhanced mitochondrial function supporting exercise capacity

L-glutamine supports the health of the digestive tract, while glutathione provides systemic antioxidant support and liver protection

doi: 10.1096/fj.201802534RR

Moreover, an increase in fibrogenic cells could further exacerbate muscle pathology by contributing to tissue fibrosis

Though the two molecules target the same receptor and share a similar chemical structure, there is enough laboratory evidence to distinguish their effects on the receptor, hormone levels, appetite control and scientific applications