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The elevated cAMP activates two primary pathways: Protein Kinase A (PKA) and Exchange Protein directly Activated by cAMP (EPAC)
[1] [2] If a GLP-1 receptor agonist is started, any existing DPP-4 inhibitor is usually discontinued
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Diabetes Care (2016) 39(10):1693701
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Umpierrez G, Tof Povedano S, Prez Manghi F, Shurzinske L, Pechtner V
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