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IBI3020, a CEACAM5-targeting ADC with an undisclosed dual payload, has also shown robust antitumor activity, notable bystander effect, and a manageable safety profile in preclinical tumor models, and has just entered a phase I clinical trial in patients with unresectable, locally advanced, or metastatic solid tumors (NCT06946446) 238

ABR thresholds were determined 3 days post-treatment at various frequencies (4, 10, 20, and 40 kHz)

6 In that study, there was no significant relationship between the percent decrease in methotrexate plasma concentration and glucarpidase dosage

- Liposomal Vitamin C is not water-soluble like other forms of the vitamin

If you've noticed your bowel movements have become less frequent or more difficult, you're not alone

We utilized site-directed mutagenesis of mouse GLRX in which one or multiple cysteines were mutated to serine (Supplementary Figs