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The new study also found that the risk of cancer diagnosis for people with type 2 diabetes was not different among those who were treated with GLP-1s compared with those where were being treated with metformin

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Two therapeutic strategies were highlighted in this review: directly inducing the ferroptosis pathway and targeting metabolic vulnerabilities that affect ferroptosis

However, the absence of adverse effects in animal studies does not guarantee safety in humans

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1417 Overall, clinical evidence regarding the effects of GLP-1 RAs on exercise capacity is limited and inconsistent, and varies across the spectrum of HF