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Clin Chim Acta 511:167176

Jul 22 2025 Gong et al., BMC Pulmonary Medicine, doi:10.1186/s12890-025-03824-5 Efficacy and safety of combined nebulization of unfractionated heparin, acetylcysteine, budesonide and ipratropium bromide in hospitalised patients with COVID-19 pneumonia: a randomized controlled clinical trial RCT 74 hospitalized COVID-19 pneumonia patients showing improved lung lesion absorption and oxygenation with combined nebulization of unfractionated heparin, acetylcysteine, budesonide, and ipratropium bromide

A standard research cycle typically spans 8 to 12 weeks , followed by an equivalent off period of 4 to 8 weeks

the catheter was flushed with heparinized lactated Ringer's solution and a volume of heparinized lactated Ringer's equal to the volume of blood taken was injected (to maintain total blood volume)

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Trends in Molecular Medicine , 11(9), 421429