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Biochem J 425:31325

WittemansLBLLottaLAOliver-WilliamsCStewartIDSurendranPKarthikeyanSet alAssessing the causal association of glycine with risk of cardio-metabolic diseases

doi: 10.1093/jpids/piw010 239 VogelA

High levels of NAC (n-acetylcysteine) supplementation have been shown to temporarily reduce homocysteine levels.[ref] Excessive supplementation with B6, methylfolate, or betaine may cause homocysteine levels to trend to the low side in some people, but this isnt well documented in research studies

Together, they may help improve sleep quality, metabolism, and cognitive health , while supporting fat loss and lean muscle growth