It works by stimulating the pancreas to release insulin when blood sugar is high, while also reducing the release of glucagon, a hormone that raises blood sugar
Zepbound is a medication that mimics the effects of GLP-1 (glucagon-like peptide-1), a hormone naturally produced in the body that plays a crucial role in regulating appetite and glucose metabolism
GLP-1 receptors are found in key brain regions, such as the ventral tegmental area and the nucleus accumbens, which are central to the mesolimbic dopamine system
Phase 2 orforglipron data demonstrated 14.7% body weight reduction at 45mg without food or water requirements, and the addressable patient expansion is estimated to grow the anti-obesity medication market by 180 million new prescription patients between 2027 and 2032
This may be related to reduced caloric intake, changes in blood sugar patterns, or direct effects on the central nervous system
No, GLP-1 receptor agonists are not licensed or recommended for treating IBS
