By mimicking the satiety hormone amylin, it promotes fullness through distinct brain pathways
That's 2 month's worth if consuming daily
Chrisman notes that from a consumer lens, GLP-1s have disrupted the weight loss and weight management space far beyond the medications themselves. He notes WeightWatchers pivot, and suggests apparel and gym companies such as Lululemon and 24 Hour Fitness could well benefit from consumers seeing weight management more holistically
doi: 10.1128/JVI.00641-08 161 KemballCCAlirezaeiMFlynnCTWoodMRHarkinsSKiossesWBet al
B., Wasan, Y., Daniel, A

Abbreviations AEs: adverse events BC: body composition BHB: -hydroxybutyrate BIA: bioelectrical impedance analysis BIVA: bioelectrical impedance vector analysis BMI: body mass index BW: body weight CT: computed tomography CVD: cardiovascular disease FM: fat mass FFM: free fat mass GI: gastrointestinal GLP-1: glucagon-like peptide-1 GLP-1RA: glucagon-like peptide-1 receptor agonist HFpEF: heart failure with preserved ejection fraction KD: ketogenic diet LBM: lean body mass MASH: metabolic dysfunction-associated steatohepatitis MD: Mediterranean diet MEAL: Muscle maintenance, Energy balance, Avoid side effects, Liquid intake MM: muscle mass MNT: medical nutrition therapy MRI: magnetic resonance imaging PUFA: polyunsaturated fatty acids RCTs: randomised controlled trials SCFAs: short-chain fatty acids STEP: Semaglutide Treatment Effect in People with obesity T2D: type 2 diabetes TNF: tumor necrosis factor VLCKDs: very-low-calorie ketogenic diets VLEKT: very low energy ketogenic therapy WC: waist circumference WHO: World Health Organization References Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, et al
