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For example, alcohol has been shown to be the most harmful drug, considering consequences that extend beyond the individual (eg, related car accidents, gun and domestic violence) [9]

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Kong, Z., Liu, R

TGF 1 and leptin activate stellate cells, inducing them to produce collagen leading to fibrosis.2123 Cirrhotic patients with DM frequently die of liver-related causes

Some patients require lower starting doses to minimize nausea