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In cases where the information provided on the item allows us to identify clinically appropriate proxy items, we may use existing items as proxies for the newly recommended items

doi: 10.1016/j.cell.2007.10.036 333 StokesJ

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6 Molecular basis of the thiamine-induced improvements in gastrointestinal disorders As mentioned above, despite the direct exposure of the gastrointestinal system to nutritional supply, this system often exhibits thiamine-responsive dysfunctions even when no known TD signs are evident in other tissues