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Some results contradict other studies, making it difficult to draw firm conclusions about the potential therapeutic benefits of intervention

Tissues were lysed by transferring them to pre-filled bead mill tubes (Fisher Scientific, 15-340-154) containing lysis buffer (Tris-HCl 100 mM and 0.5% Triton X-100, pH 8) containing Halt Protease and Phosphatase Inhibitor cocktail and homogenized using a bead mill (VWR) for 10 s

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Nat Rev Clin Oncol 15(5):310324 Georganaki M, van Hooren L, Dimberg A (2018) Vascular targeting to increase the efficiency of immune checkpoint blockade in cancer

No severe allergic reactions, anaphylaxis, or systemic inflammatory responses have been documented in available case series