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It also obtained approval from the institutional review board at Kaohsiung Veterans General Hospital, under the identifier KSVGH21-CT1-43

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This is a classic negative feedback loop

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Lipid peroxides released early during ferroptosis act as damage-associated molecular patterns (DAMPs), promoting dendritic cell (DC) maturation and antigen cross-presentation, which in turn primes CD8 + T cells and enhances anti-tumor immunity ( + T cells and DCs, thereby positioning CDH4 as a promising target for combination therapies leveraging ferroptosis and immunotherapy

GlyNAC supplementation improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, aging hallmarks, metabolic defects, muscle strength, cognitive decline, and body composition: implications for healthy aging