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Cautions: Dose should be adjusted in chronic kidney disease (eGFR 30 to 59) and avoided when eGFR is below 30

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When comparing data from rodents with humans, results regarding GLP-1s renal effects are very different

ABSTRACT: Glucagon-like peptide-1 (GLP-1) receptor agonists are an increasingly popular class of glucose-lowering agents for the treatment of type 2 diabetes (T2DM), owing to their robust glucose-lowering effects, low risk of hypoglycemia, and potential to induce weight loss

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