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Journal of Neuroscience Research

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Involvement of Peripheral Mast Cells in a Fibromyalgia Model in Mice

Our mechanistic investigations revealed that intracellular GSSG elevation sensitizes hepatocytes to TNF killing by inducing IKK--SSG formation, leading to suppressed NF-B activation

The Nrf2/HO-1 pathway plays a vital role in antioxidative and iron-homeostatic responses, exhibiting a well-documented double-edged sword effect in ferroptosis regulation