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The Nrf2 pathway plays a context-dependent role in this axis

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DOI: 10.1196/annals.1320.010 Pennisi M, Malaguarnera G, Di Bartolo G, et al

Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma

But the FDA recently approved a pill form of semaglutide (Wegovy), marking the first time a GLP-1 pill was cleared in the U.S