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Pseudotime results are consistent with a trajectory along the vein-to-artery axis, extending from the venous side through the Esm1 + population into the arterial domain (Supplementary Fig

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Huang et al., 2015) indicates its essential application in the other tissues healing, particularly, the muscle (Figures 912), tendon (Figure 12), ligament, and bone (Figure 13) (Sikiric et al., 1993