Differential effects of once-weekly glucagon-like peptide-1 receptor agonist dulaglutide and metformin on pancreatic -cell and insulin sensitivity during a standardized test meal in patients with type 2 diabetes
At this stage, it is more accurate to describe these psychological and QoL improvements as concomitant effects of metabolic and symptomatic relief rather than independent psychopharmacological actions
Ensure you are eating small, protein-rich meals and staying well-hydrated, as dehydration amplifies nausea
Therefore, a RCT designed specifically to compare combination therapy with monotherapy is essential to draw definitive conclusions
8 Limitations and evidence gaps Key gaps include limited long-term randomized clinical trials, variability in intervention timing and dosing, and insufficient stratification by age, sex, chronotype, and comorbidities
In pwIIH, papilledema can be detected and monitored by measuring the pRNFL thickness