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Absence of Hypertrophy Markers BPC-157 did not increase cardiac mass (heart weight normalized to body weight) in any chronic rodent study identified in the literature, which distinguishes it mechanistically from anabolic steroids and growth hormone, both of which produce pathological cardiac hypertrophy with prolonged use

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But no published trial has shown retatrutide preserves lean mass better than GLP-1/GIP agents

310 , R885R895 (2016)