GREAT: Mediterranean & Greek Restaurants Examples: Zoes Kitchen, Naf Naf, local Greek restaurants Why they work: Grilled proteins are the specialty Vegetable-forward cuisine Olive oil instead of heavy cream Protein plates with simple sides Strategy: Order chicken or lamb kebabs, Greek salad with protein, or grilled fish plates
Who Should NOT Take GLP-1 Medications Being honest about who isnt a good candidate is part of providing responsible care
Discussion Human data on the fetal effects of maternal GLP-1 agonists and SGLT2 inhibitors are scarce
The speed of orforglipron's clinical development from Phase 1 to regulatory submission, spanning approximately 5 years from first-in-human dosing to FDA submission, represents one of the fastest development timelines in obesity pharmacotherapy history
J Control Release 2020;325:11120.PubMed 16
These findings may ultimately expand the indications for GLP-1RA therapy and solidify their role in precision CV risk reduction, for example in different subphenotypes of prediabetes and T2D
