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doi: 10.1038/nbt1210-1248 102 WhangerP

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460,461 scRNA-seq data reveal the extent of heterogeneity in CSCs, including differences in gene expression, mutations, and functional properties, enabling the identification of subtypes with distinct responses to therapy

The difference between those two use cases is what most general guides fail to distinguish

Erythrocytes: structural features (lack of organelles) determine the cell death signaling pathways Unlike normal nucleated cells, mature erythrocytes are hemoglobin-filled, flexible, thin nucleus- and organelle-free entities of biconcave shape with a size of 78 m [29]