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In this study, they found that DNA polymerase (Pol ) regulated RA pathogenesis through STING-NF-B signaling-induced macrophage pyroptosis (65)

The enzymes tryptophan-2,3-dioxygenase or indoleamine 2,3-dioxygenase 1 and 2 (IDO1 and IDO2) catalyze the degradation of tryptophan to N-formylkynurenine, which is a key step of the kynurenine pathway, followed by subsequent conversion of N-formylkynurenine to kynurenine, 3-hydroxykynurenine, quinolinic acid and picolinic acid [269]

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SELENOS, selenoprotein S

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