Should we pretend that mechanistic plausibility plus consistent clinical observation equals zero evidence
Originally used in medicine as an anti-hemorrhagic agent, its skin brightening potential was discovered by accident
GLP-1s was originally created to help treat type 2 diabetes, as it helps regulate blood sugar
The reason may be that zinc methionine can be directly absorbed by the small intestine through the amino acid transport system, bypassing some of the complex absorption processes of inorganic zinc
PH was supported by NIH Grant K 12 HD105271, University of California San Diego Altman Clinical and Translational research institute (ACTRI)/NIH grant KL2TR001444, and Pinacle Research Award in Liver Disease Grant #PNC22-159963 from the American Association for the study of Liver Diseases foundation
The large, randomized trials that have been done with GLP-1 receptor agonists versus placebo show no signal for pancreatitis