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Cytokine (2020) 133:155146
This led researchers to hypothesize that GLP-1 mimics drugs like semaglutide and might alter the way our brains respond to addictive substances
Mutations in critical transporter and enzyme genes disrupt these steps and underlie a spectrum of neurological disorders collectively termed riboflavin-responsive neurometabolic diseases. A representative example is riboflavin transporter deficiency (RTD), caused by loss-of-function mutations in SLC52A2 and SLC52A3 , which encode the riboflavin transporters RFVT2 and RFVT3, respectively
Theoretically, yes, you can take a break from Wegovy, but its unlikely to be recommended by clinicians as youd need to drop back down to the lowest dose should you decide to go back on the medication