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[3] [9] The mechanism of action involves binding to both GIP and GLP-1 receptors, which are naturally occurring incretin hormones

GLP-1 exerts its anorectic effect in part by acting on the hunger-satiety centre located in the arcuate nucleus of the hypothalamus, and in part by delaying gastric emptying

Not only that, but polyphenols can utilize the structural characteristics of hydroxyl groups on their benzene rings to scavenge free radicals through H atom transfer (Papuc et al., 2017)

Challenges of GLP-1 Agonists Despite their promising benefits, GLP-1 receptor agonists are not without limitations

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