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10.1016/j.tibs.2015.11.012 13 BrashA

Indeed, it was clearly shown that the antioxidant N-acetyl-L-cysteine (NAC) can inhibit eryptosis in vitro [116] and significantly prolong the half-life of circulating mouse erythrocytes in vivo [72] presumably by interfering with efferocytosis of eryptotic cells

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Additional studies could be directed toward optimizing delivery techniques, dosing schedules, product stability, and intranasal formulations

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Generation of GFP-tagged cell lines HepG2-GFP reporter cell lines expressing tagged Nrf2, HMOX1, or SRXN1 were constructed with bacterial artificial chromosomes that encode C-terminal GFP-tagged fusion proteins as described previously (Wink et al