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Zhao et al., 2014)

No se recomienda su uso si se padecen enfermedades renales, especialmente si se encuentran en dilisis

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The resulting metabolic disturbances cause myocardial lipid accumulation, mitochondrial dysfunction, and ROS accumulation, manifesting as cardiac hypertrophy, reduced contractile function, and impaired exercise tolerance, establishing TMAVA as an independent cardiovascular toxic molecule

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