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The most serious side effect is the risk of birth defects to an unborn fetus

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and the combined treatment of a glycolytic inhibitor in conjunction with the silencing of anti-apoptotic proteins such as myeloid cell leukemia sequence 1 protein (MCL-1) can enhance the antitumor activity in cells resistant to prednisolone (Aris et al., 2013)

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Seminars in reproductive medicine