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1-2 weeks Appetite and cravings start to decrease 2-6 weeks Noticeable weight loss begins 4-8 weeks Insulin sensitivity improves 3-6 months Testosterone levels begin to drop, and periods become more regular 3-12 months Fertility markers start to improve Even if you decide to take a GLP-1 medication, changing your lifestyle and habits are still essential to see long-term success with balancing your hormones, naturally supporting GLP-1 production, and weight loss

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JAMA 2015;314:68799.ArticlePubMed 44