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Some agents in this class have also demonstrated cardiovascular and renal outcome benefits in clinical trials
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Yosipovitch G, Sackett-Lundeen L, Goon A, Yiong Huak C, Leok Goh C, Haus E (2004) Circadian and ultradian (12 h) variations of skin blood flow and barrier function in non-irritated and irritated skin-effect of topical corticosteroids
10.1038/srep45680 5 AndersenA.LundA.KnopF
An up-to-date account on co-activator involvement in diverse disease phenotype and several therapeutic strategies like small molecule inhibitors, molecular glue degrader and PROTACs for targeting the activity of these co-activators have been discussed extensively in this review