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The Food and Drug Administration (FDA) approved on Thursday a first-of-its-kind oral option that can lower "bad" LDL cholesterol with a daily pill instead of a shot
Its primary mechanism is angiogenesis: BPC-157 helps trigger new blood vessel growth in injured tissue, which is what allows it to support repair in tendons, ligaments, the gut lining, and joints
Six controlled trials in approximately 900 participants are summarized in Stier et al
The report was uncontrolled, unblinded, not randomized, had no comparator arm, used patient-reported outcomes rather than validated pain instruments, and did not publish dose, effect size, confidence intervals, p-values, or systematically collected adverse events limitations that severely constrain any clinical inference
doi:10.1134/S207905701901017X
We need more research in this area
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