24) showed that SeC@PA(+) significantly upregulated the levels of phosphorylated JAK (p-JAK1) and phosphorylated STAT6 (p-STAT6) but had no significant effect on phosphorylated ERK (p-ERK) levels, indicating that SeC@PA(+) activation occurred via the JAK-STAT6 pathway (Supplementary Fig
Rocha RL, Hilsenbeck SG, Jackson JG, Lee AV, Figueroa JA, Yee D
Schapira AH
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Kevin Klatt, PhD, RD, an assistant research scientist and instructor in the Department of Nutrition Sciences and Toxicology at University of California, Berkeley, cautions that epidemiological studies using circulating levels of nutrients or metabolites as proxies for dietary exposure often dont correlate with randomized controlled trials that aim to increase levels of those nutrients or metabolites
Physiol Rev, 1998