Hypoglycemia: While less common with GLP-1 receptor agonists like semaglutide compared to some other diabetes medications, hypoglycemia (low blood sugar) can still occur
It is important to note that Zepbound is not approved to treat type 2 diabetes under this brand name, even though its active ingredient (tirzepatide) is used in diabetes care under a different brand name (Mounjaro)
Eating and Drinking to Support Movement Scientific American reports that the only way to reduce muscle loss somewhat during weight loss is to combine exercise with a higher-protein diet. The same source explains that adults normally aim for about 0.8 grams of protein per kilogram of body weight per day, but that people exercising during weight loss may need 1.21.5 grams per kilogram to preserve muscle. Hydration is also important
Medical Conditions That May Qualify You If your BMI is between 27-29.9, you may still qualify for GLP-1 medications if you have: Type 2 diabetes or prediabetes High blood pressure (hypertension) High cholesterol or dyslipidemia Sleep apnea Cardiovascular disease Metabolic syndrome Insulin resistance These conditions are often interconnected with weight, and GLP-1 for weight loss can help address multiple health concerns simultaneously
4b) during the initial phase of treatment
Liraglutide was approved without a CVOT (Cardiovascular Outcome Trial) because authorities accepted the results from the LEADER study, designed for superiority