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This is well known to clinicians and easily monitored

however, as yet, no inhibitor with pharmacological potential has been identified

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doi: 10.1016/0006-291X(92)92355-2

However, the expression of AADAC in rat tissue is seven-fold lower than the expression in human tissue 18 which may account for the absence of observable flutamide hydrolysis in this rat S9 model