what are the disadvantages of oral semaglutide

what are the disadvantages of oral semaglutide Comparative Effectiveness and Safety Versus Subcutaneous in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis Understanding Oral Vs. Injectable Semaglutide:

Name: what are the disadvantages of oral semaglutide Comparative Effectiveness and Safety Versus Subcutaneous in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis Understanding Oral Vs. Injectable Semaglutide:
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Description

Its primary structure is a 39-amino-acid peptide with a C18 fatty diacid moiety, designed to extend its half-life and allow for prolonged receptor recruitment

As such, we did not consider open-label status as a source of bias, given that measurement of HbA 1c is an objective outcome and thus is not affected by blinding status [15]