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Obesity is recognized as a chronic disease that can increase the risk of diabetes, heart disease, stroke, and other serious health conditions
A meta-analysis [74] including the ELIXA [66], LEADER [44], SUSTAIN-6 [67], EXSCEL [68], REWIND [70], and AMPLITUDE-O [51] studies found that GLP-1RAs were associated with better renal outcomes: a 30% or 40% or more decrease in glomerular filtration rate, need for renal replacement therapy, end-stage renal failure, or death from kidney disease by 21%
doi: 10.1111/dom.14126
(9) Bone resorption is accomplished through the enzymatic activity of osteoclasts
Bruyre O, et al